Warning on rising Med Sea levels. Levels in the Mediterranean Sea are rising rapidly, with potentially serious effects in coastal areas, a study finds. [BBC News | News Front Page | World Edition]

That is 10 cm a decade or half a meter in 50 years. That is a huge amount if you are close to the water.  11:09:38 PM    

Cognate CD4+ T cell-dendritic cell interactions induce migration of immature dendritic cell through dissolution of their podosomes.

Dendritic cells (DC) control T cell-based immunity. To do so they need to mature and migrate to sites of T cell priming. We have previously shown that cognate interactions of human CD4⁺ T cells with DC induce DC maturation. We show here that CC chemokines produced during antigen-specific T-DC interactions also induce strong morphological modifications and migration of immature DC. These modifications are required for efficient T cell activation. Moreover, we show that CC chemokines produced during antigen-specific DC-T cell interactions induce the dissolution of structures involved in cell motility and present on immature DC, i.e. podosomes. We thus propose a model in which chemokines secreted during Ag-specific contact between T cells and DC induce disassembly of interacting and neighboring immature DC podosomes, leading to recruitment of more immature DC towards sites of antigenic stimulation and to amplification of T cell responses.

[BLOOD First Edition Papers]

Have to check this out.  10:11:03 PM