You know you want to think the big thoughts. Here's some fuel, some food for thought.

A New View of Our Universe: Only One of Many

Many Universes, Several Theories

Or perhaps the very small thoughts?

Smile, Electron! Fast 'Camera' Captures Action

Or, a little closer to our frame of reference, consider what we don't know about sex, gender, and sexuality:

The Ambiguities of Sexuality

[all via the New York Times]

12:32:06 AM