Monday, April 26, 2004

High-Dose Cyclic Antidepressants Linked With Risk of Sudden Cardiac Death
Reuters Health story at Medscape - "The risk of sudden cardiac death is not increased with selective serotonin reuptake inhibitor (SSRI) antidepressants, or tricyclic and other related cyclic antidepressants (TCAs) in doses less than 100 mg, according to results of a study published in the March issue of Clinical Pharmacology and Therapeutics. However, there appears to be an association between higher doses of TCAs and increased relative risk." "med"  
  

Developments in the Treatment of Cannabis Use Disorder
Article from Current Opinion in Psychiatry at Medscape that describes recent developments in the treatment of cannabis abuse and dependence in the general and special populations - "There is a paucity of research into pharmacological and psychological interventions for cannabis use disorder. There are no accepted pharmacotherapies available. Whereas relatively brief cognitive-behavioural therapy has the strongest evidence of success for adults with cannabis dependence, among adolescents involved in the juvenile justice system and those with severe, persistent mental illness, longer and more intensive therapies provided by interdisciplinary teams may be required..." [Viewing Medscape resources requires registration, which is free].