(US-Minnesota-Minneapolis) Local medical technology company is seeking a Senior Principal Scientist to manage their research studies aimed at the development of cardiac pacing leads. This includes experimental design, animal and human experimental protocol development, fulfilling appropriate legal requirements, data analysis, documentation and publication of results. This position will work with customers, consultants, researchers, marketing, and product planning. In addition, the position is responsible for ensuring new concepts or features are successfully transferred to new products. Must have a Masters degree in Physiology or Biomedical Engineering, PhD. is preferred.
(US-Connecticut) Pharmaceutical company position with great salary and benefits. Board Certified in Infectious Diseases. Experience with HIV clinical studies Phase IIIB and IV.
(US-Michigan-Ann Arbor) This individual will lead the Product Process Development group and drive the implementation of world class processes for the development and production of the company’s biopharmaceutical and small molecule product candidates. Responsibilities include working with the management team to develop strategies for prioritizing and implementing best product process development plans and practices for the various product areas. The Director will also be responsible for developing a strategic plan and tactical methodology for scaling up production of product candidates to support clinical trials, and eventual commercialization and distribution to market. This person will be expected to help lead the negotiations with potential partners, suppliers, and technology vendors as necessary to scale up production. Then ideal candidate will have a minimum of 10 years experience in working with external CMO’s for product process development. Candidate will also have demonstrated expertise in developing processes to support complex production methods and proficiency working with both large and small molecule production. The successful candidate will be hands-on, dynamic, self-motivated, and have and engineering mindset with a focus on product process development and implementing processes. The ability to work within critical timelines is essential, as are planning, communication and leadership skills. Requirements include a post-graduate degree in engineering, science, or related field and 10 years of industry experience.
(US-Maryland-Montgomery County) Responsible for responding to advanced scientific and data management questions (escalated from Tier I) from users and developers requesting assistance with specific proprietary applications/tools. Duties and Responsibilities ·Provides advanced phone and e-mail support to users, software developers, and system administrators for custom applications developed for /by clients ·Troubleshoots and responds to advanced scientific and data management questions related to core applications as well as advanced system configuration and administration questions. ·Assists bioinformatics developers in expanding/enhancing research studies and conducting independent research and development experiments using proprietary applications and tools. ·Creates sample code, examples, and documentation as required for individual users/developers and general training use. Required Technical Expertise: ·Master’s degree in Bioinformatics, Computational Biology, or related field. ·Knowledge of standard software applications for PCs, Macs, and UNIX systems and development platforms such as Apache, Tomcat, and Zope. ·Demonstrated programming skills with solid Java, Perl, and web development experience. ·Experience with other languages/technologies is a plus – especially J2EE (servlets, JSP), Visual Basic, PYTHON, RMI, JavaScript, WebServices, SOAP, XML, UML, SQL, and Oracle Clinical. ·Significant knowledge of and interest in genetics, clinical trials, sequence analysis, microarrays, and laboratory information management systems. ·Excellent oral and written communication skills. ·Pragmatic problem solver with superior interpersonal skills, cooperative and professional demeanor, and enthusiastic customer service orientation.
(US-Massachusetts) SciGenium is looking for an Up Stream - Scientist in the Boston Area. Responsibilities: Process scale-up of a Mammalian cell facility for a recombinant Protein - blood product. Emphasis is on upstream process development work i.e. BioReactors- perfusion, aspiration. Previous experience growing the cells cleanly and efficiently up to 500 liters as well as downstream purification. Work in a Scale-up manufacturing environment operating under cGMP as well as experience from process transfer to Manufacturing. Utilize your knowledge of purification development principles for polysaccharides as well as ability to perform routine in-process and release assays. Work with Bioreactor to created biologics, purified proteins and ability to assist in cell / tissue culture as well as associated knowledge/technology transfer issues. Will perform protein characterization via spectroscopy (FT-IR, CD, fluorescence, or Raman). Requirements: Phd and 5+ years commercial exp in accordance with cGMP and FDA guidelines Good working knowledge of SOPs, GLPs, and SSPs.
Objective: An entry-level Sales position at a Biotechnology/Pharmaceutical company in Canada. Education: 1998-2003 St. Hugh’s College, Oxford University, England MBioch (Oxon) - Molecular and Cellular Biochemistry (Honours) 1993- 1998 Harrow School, London, England
Objective: Looking for an entry-level position, in the field of Biotechnology, which will give opportunity for career growth and full utilization of my skill. Techniques known: Protein /Peptide synthesis, Southern blotting, High performance liquid chromatography, Gel –doc system, SDS-PAGE, Gene cloning techniques, ELISA, Ion exchange chromatography, Tissue culture techniques, Polymerase chain reaction
Objective: A chance to learn and to develop my skills and to create a niche for myself in the field of Bioinformatics. Research experience TITLE: Expression Profiling of Lung Cancer Genes. ORGANISATION:Ocimum Biosolutions (India)Ltd(Hyd). DESCRIPTION:Using oligonucleotide microarrays the expression of 12,600 genes in lungcancer were studied. This lead to classification of lung cancer into different subtypes. After data reduction using Genowiz the significant genes involved in small cell lung carcinoma were studied and mapped to biologial pathways using GenMAPP,KEGG, and gene ontology.Their effects over the immune system were studied.This helped us to develop specific drugs as well as to understand the exsistence of different subtypes. TOOLS:JAVA, Gen MAPP, Gene Ontolog, KEGG, NCBI.
Objective: To reach the cutting edge of the technologies. Experience: 6 Years in MS Technolgies Education: MCA from IGNOU University Skills: ASP, SQL Server 2000, VB, PHP, MySQL.
Objective: to able to procure a job a job as a dental medical salesperson Experience: owned and managed my own dental office for 12 years; Funeral Director for 2 years selling over$72,000/month of Funeral Service Merchandise. Education: BS Biology and Chemistry Mount St. Mary's College 1983 Magna Cum Laude Doctorate of Dentistry Fairleigh Dickinson University 1987 Degree in Funeral Service American Academy McAllister Institute 2000 Magna Cum Laude
Objective: To contribute my education and technical skills in the field of Biotechnology Experience: - 2003(Jan-July) Project Assistant.Department of Microbial Technology,Madurai Kamaraj University,Madurai,India.Work on "Isolation and Characterization of the Triterpenoid Beguiling acid from Heteropogon contorts. Assaying of the antimicrobial activity of Beguiling acid against E coli, Staphylococcus aureus, Aspergillus versicolor" - 2003 (Oct-Jan)Project Assistant.Institute of Bioinformatics,Hyderabad,India.Work on "Is Gene Clustering universal in Bacteria" - 2002(July-Dec)Teaching Assistant.Madurai Kamaraj University,Madurai,India.Worked as a Teaching Assistant teaching Biochemistry ,Molecular Biology. - 2002 (May - July)Project Trainee.Avastagen Biotech Company,India.Work on "Isolation of a Apoptosis Inducing Ligand TRAIL from Human Placental tissue and detection of its Apoptosis Inducing potential on Cancerous cell line Hela cell lines"
Objective: Full time position as biostatistician, or bioinformatics developer. Experience: Summer Scholar at Lawrence Livermore National Laboratory (Summer 2000, 2001, 2002, 2003) ·Worked closely with computer scientists to design and implement working prototype of pathogen DNA signature development system referenced in above publication. ·Designed and implemented statistical data analysis infrastructure, including a database, analysis techniques, and analysis code, for project that analyzed how much sequencing is required for high-quality pathogen DNA signatures. ·Numerous other projects involving statistics, computer science, software engineering, and biology.
Experience: - LIFE SCIENCES CENTER, UNIVERSITY OF BRITISH COLUMBIA, Vancouver 2003 Project Group Leader - CHAI-NA-TA CORP., Vancouver, Portland, Hong Kong, Shanghai 1993-2002 Director of R&D/Manager of New Business Development 1998-2002 - Manager of R&D/Overseas Joint Venture Representative 1995-1998 - Manager of Product Development 1994-1995 - New Product Development Consultant 1993-1994
Objective: A position where skills in biology will be used. Experience: - Fall 2003-Spring 2004 UNC at Greensboro Greensboro,NC Researcher Researched on the affect of ATP on Na, K-ATPase in Duck enzyme using fluorescence spectroscopy - Fall 2002-Spring 2004 UNC at Greensboro Greensboro,NC Teacher for Major Concepts in Biology Lab Instructed students on how to carry out various experiments such as on data analysis, macromolecules and nutrition, the circulatory and respiratory systems, molecular genetics and Biotechnology, mitosis, meiosis, human genetics, biodiversity and taxonomy
Experience: - 10/2002 -- PRESENT LOCUM TENENS PHYSICIAN - 10/1/2001 – 9/01/2002ATTENDING PHYSICIAN MOUNTAIN VIEW URGENT CARE CLINIC & FAMILY PRACTICE CLOVER, SC – 29711 - Jan ’98 – 10/12/01 ATTENDING PHYSICIAN Department of Internal Medicine Tourney Regional Medical Center
Objective: research Experience: 03/95- 07/97 Research Associate, Novosibirsk Institute of Bioorganic Chemistry. Development of the method for lactoferrin purification and ELISA test. Education: - 01/03- present Post-Doctoral Research Associate, Biochemistry Department, Medical College of Wisconsin, Project title: Elucidation of structure-function relationships in mevalonate diphosphate decarboxylase, a cholesterogenic enzyme. - 06-07, 2001 Summer school on protein folding, structure and design, ICTP, Trieste, Italy - 09/97- 12/02 PhD, chemistry, Department of Chemistry and Biochemistry, University of Wisconsin – Milwaukee. Dissertation title: Effect of toxic metals on transcription factor IIIA: finger 3 peptide folding and interactions with DNA.
Skills: Animal Handling and Injections, Immunohistochemistry, Light Microscopy, Rat brain and hippocampi extractions, Recombinant DNA, Tissue and cell culture, Transformation of bacteria, PCR, DNA gel electrophoresis, Perfusion, Protein extraction, Western Blotting, SDS-PAGE
Experience: - Karmanos Cancer Institute, Wayne State University, Detroit, MI (February 2000- present) Research Assistant Responsible for assay set-up, development and implementing DNA and protein microarray technology (cDNA & Affymetrix). Phage display technology. Protein microarrays (spotting and assay set-up). Data mining & analysis, bioinformatics. - IntelliGene Expression, Inc., Edmonton, AB (1997- 2000) Research Assistant Responsible for daily duties in QC laboratory; Western blot, conductometry, HPLC, GC.
Experience: 5 years of Business Development in the IT and Biotechnology Industries with ‘on-the-field’ experience in target oriented direct marketing, pre-sales, relationship/ account management, market research, new business/market identification, channel partner and business partner management at the international (USA, APAC and the Middle East) and national levels.
Objective: To work at a drug industry on a challenging project using my scientific and computational skills Experience: Differential expression of proteins during stress (Jan 2002 – May 2003) Graduate Student in the Department of Biochemistry and Molecular Biology, Indiana University Medical School, Indianapolis, IN. ICAT (Isotope coded affinity tag) technology was used to measure and compare two yeast cultures that were grown in different states: non-stressed and Rapamycin-treated conditions. The ICAT strategy relies on in vitro derivatization with biotinylated tags of protein obtained from both the strains, followed by mixing of the tagged proteins, enzymatic digestion and purification by affinity capture-based release of peptides containing the tags. Proteins originating from stressed and non-stressed conditions were distinguished by using tags containing light and heavy stable isotopes (for example, deuterium) so that the tagged peptides produced by digestion have a different mass. Identification and quantitation of several proteins were successfully achieved by data analysis obtained from mass spectroscopy.
SKILLS IN THE FOLLOWING AREAS: - Mammalian molecular biology, including transfection, cloning, gene expression analysis (Western blot, RT-PCR, Q-PCR, Northern blot), DNA/RNA isolation; Affymetrix Gene Chip array technology, the laser capture microdissection microscopy and the fluorescent microscopy. - Mammalian cell biology, including experience with human and murine cell culture, experience with techniques such as ELISA, immunochemistry, cellular assays of proliferation and cytotoxicity, invasion assay, apoptosis-assay (DNA fragmentation, TUNEL assay), experience working with standard and confocal imaging systems. - Biochemistry, including electrophoresis (SDS-PAGE, agarose gel) and biochemical tests (serum proteins electrophoresis, total serum protein and serum creatinine; lipoprotein electrophoresis, the major serum lipid, serum triglycerides, total serum cholesterol, serum esterified cholesterol, LDL-cholesterol and HDL-cholesterol; serum glucose, serum glutamic oxalacetic transaminase, serum glutamate pyruvate transaminase, serum lactate dehydrogenase and serum amylase ). - Animal models including experience working with healthy and cancer-bearing animals (primarily mice and rats), able to administer different types of drugs via parenteral routes and able to perform different types of surgery; biocompatibility and hematological tests (WBC, RBC, Hb, Ht and red cell indices) and immunizations.
Objective: Seeking a challenging position with scope for research in the design and development of devices with (biological & chemical) sensor and clinical diagnostic applications. Experience: The Institute for Lasers Photonics & Biophotonics, University at Buffalo, Buffalo, NY - Graduate Research Assistant, June 2002 - present - Currently making highly sensitive fiber optic probes with applications in chemical and biological sensing. - Working on Evanescent optical detection systems with applications in other biological detection systems. - Specialized in the chemical etching, handling and connectorization of optical fibers including D-fibers and tapered fibers. - Experience in bioassays including bonding of proteins (antibodies) on glass substrates for use in the biosensor. - UV-visible and fluorescence spectroscopies. - Perform data (spectral) acquisition and device characterization.
Objective: Utilize my experience of 17 years in the medical and Pharmaceutical field to promote quality products that really make a difference in the life of an individual Experience: - 7 years of Sales and managemnt of a specialty pharmaceutical injectable used in the Dialysis market. - 7 years of sales in capital equipment in the medical field
Objective: A position in clinical research where I will utilize my ability to build relationships with clinical site staff. My skills as a detailed-oriented and organized monitor will ensure that clinical trial protocols are followed accurately with integrity. Experience: Wyeth Research in Marietta, PA Scientist, Vaccine Development (VD) (2000 - 2003) Performed GMP release testing for potency of clinical and unformulated materials. Trained and qualified QC Virology and VD personnel in the assays and equipment. Revised technical SOPs, protocols and reports. Developed and validated viral assays. Supported the implementation of quality systems in the VD labs. Transferred the assay to the QC Virology Department. Maintained and reviewed official records and practiced laboratory procedures using cGMP standards as governed by company and federal policies.
Skills: ·Extraction of genomic DNA of plants according to micro C-TAB procedure (modification of Doyle’s and Doyle’s procedure, 1987) ·Estimation of quality and concentration extracted DNA through spectrophotometrical measurement ·Performance of AFLP procedure including: digestion of DNA with restriction endonucleases, reaction of ligation, reaction PCR ·Practical and theoretical ability of solving molecular problems – the key role in graduate researches was modification of AFLP technology for Arabidopsis thaliana (L.) Heynh. ·Performance a polyacryloamid and agarose electrophoresis ·Operation standard equipment of molecular laboratory (e.g. thermocyclers, thermomixers, GeneQuant™ ) and ability to operate the automatic sequenator LI-COR IR2
Experience: 2001 - present HP (Hewlett Packard, Inc.) Houston, TX - Engineering Manager IV (Expert) - ISS Division (Servers) Managed software development and QA, schedules and interface relationship between development/QA teams in the United States, at HP vendors and with a Taiwan outsource partner for the ProLiant two-way server families including the ML310, ML350G3, ML350G2, ML330G2 and DL320G2. Member of the core development teams for these servers representing Software Development/QA. Managed cross-functional teams - ROM, storage (SCSI, PATA, SATA, RAID), NIC, server management, regulatory (e.g., WHQL), marketing, training, QA, and remote Taiwan outsourcing teams. Managed MSFT, Novell, and Linux OS development/QA teams. Member W2K3 SBS core team. I lead the strategy and advanced OS development and certification teams. Contributed to several major process improvements including platform-to-portfolio paradigm changes. Lead advanced cross-functional core team implementing next-generation architectures and support development.
Experience: Developmental Biology Laboratory Technician, The Jackson Laboratory, Bar Harbor, ME; May 2003 – present Designed and executed multiple methods for exploring the sex determination pathway in mouse models. These include how to quantify the gene expression of 100 genes in fetal gonads using Real-time PCR and removing the expression of candidate genes in specific tissues using Cre/LoxP recombinase technology. Instructed other lab members on how to design and execute further experiments and was responsible for purchasing capital and reagents to exceed our goals.
Skills: - Personal Skills: Analysing problems and evaluating ideas and suggestions; team-working, i.e., the ability to be flexible and adaptable to different people and situations; innovation and creativity, i.e., generating new proposals and solving complex problems. - Laboratory Experience: Tissue/cell culture techniques; polymerase chain reaction (PCR); sequencing; luciferase assays; scintillation proximity (SPA) assays; b-galactosidase assays; cAMP assays; cGMP assays; confocal immunofluoresence microscopy; Cytosensor microphysiometry; FLIPR; DNA/RNA isolation. - Computer Literacy: Microsoft Word; Microsoft PowerPoint; Microsoft Excel; Graphpad Prism; SPSS; STATA; CorelDraw; Adobe PhotoShop; Endnote; Reference Manager9; CakewalkPro8; CuebaseSL; working with Microsoft Access-based databases; Sebelius.
Objective: Looking for clinical or basic biomedical/pharmaceutical research job or postdoctoral position in different fields of clinical, experimental biomedical, and pharmaceutical sciences, and/or health or research administrative job. I have in depth long experiences in pharmaceutical and clinical sciences, research, teaching, distance learning, laboratory instrumentation and health administration. I have wide range of abilities allowing me to seek job with different responsibilities.
Objective: Energetic, creative, experienced and highly motivated research scientist with technical, supervisory and project management skills to drive your company’s ability to deliver high-quality science. A scientist with outstanding expertise in molecular biology, genetics, and genomics seeking challenging position in a biotech/biopharma company. Experience: Well experienced in human genetics including breast cancer, molecular diagnostics and assay development. Expertise in many modern molecular techniques including microbial and mammalian vector development and construction; embryonic stem cell and oligodendrocyte transformation and culture; establishment and maintenance of transgenic mouse lines; bisulfite genomic sequencing; methylation Specific PCR (MSP); genomic library screening; dideoxy DNA sequencing; PCR, including RT, inverse, bubble technique, semi-quantitative PCR, real time PCR and real time quantitative RT-PCR; Isothermal Amplification; Southern hybridization; Dot blot; genomic and plasmid DNA purification; molecular cloning and recombinant DNA; computer-assisted sequence manipulations; animal brain surgery; cell implantation; immunohistochemistry and ELISA.
Objective: A position in clinical research field. Experience: FMC Corporation. Princeton, NJ. 2003 (Present) Compound Acquisition Coordinator Coordinate the acquisition and internal cataloging of appropriate amounts of all compounds required by Chemical Synthesis Project Teams. Ensure that all compounds are registered in the standard format. Work with chemists to maintain a consistent and orderly terminology, so that the database accurately reflects the on-site supply. Render vendor supplied files compatible with the on-site ACQUIS/ISIS database. Understand the structural categories of chemicals within the database as well as the history and contractual obligations associated with various chemical suppliers. Locate and distribute standards, analogs and experimental samples requested by Project Teams in a timely fashion. Ensure that samples provided to Screening Teams are in the appropriate format. Participate in efforts to expand compound handling capabilities in site-wide research.
Objective: Clinical Research Associate position that will utilize my research and administrative skills. Experience: 2002-2003NASA AMES RESEARCH CENTER: EDUCATION ASSOCIATES PROGRAM Moffet Field, CASTUDENT RESEARCHER - BONE LAB Performed primary lysis of Rat Osteoblast (ROB) cells and macrophage cells. Conducted all aspects of 1-D and 2-D Gel Electrophoresis including technique development, gel run completion, proteomic analysis and trouble shooting. Performed Western Blots.
Objective: Leadership management role in Methods & Applications for Research Operations & Data Management: Assessment & Technology Development, New Applications & Computer Adaptive Testing. Senior executive specializing in the design of advanced information systems and their deployment throughout the enterprise. Experience: Experienced Senior Technology Executive with expertise in hardware and software development, systems design, program management, marketing and consulting services. Successfully delivered new technology solutions in startup and Fortune 100 environments. Strengths in collaborative team-building across business units and between companies. Ability to quickly analyze a business or market need and implement a prioritized action plan. Proven track record in building organizations and driving complex projects to completion and profitability.
Objective: To work in an industry setting and perform applied physiological and clinical research in order to obtain a better understanding of and finding potential treatments for human diseases. Experience: My research interests and expertise is in the area of animal models of metabolic diseases. My present project focuses on elucidating some of the molecular mechanisms involved in regulating skeletal muscle growth and development. A better understanding of these processes is essential for potential therapeutic manipulations to ameliorate skeletal muscle atrophy as a result of normal age progression or muscle-degenerative diseases.
Objective: A challenging leadership position in a research team that will offer room for advancement in the field of exploratory drug discovery and assay development Experience: 2002 - 2003; University of Colorado Health Sciences Center, Denver, CO. Research Associate - Isolated and characterized the Hepatitis C virus ribonucleoprotein complex and determined the interaction of cellular factors such as PTB (polypyrimidine tract-binding protein) with the replicase complex. Used Hepatitis B virus (HBV) as a model for regulation of liver-specific gene expression, particularly to determine the response of several transcription factors (whose activities are modulated by oxidative stress) to the HBV encoded regulatory protein HBx; evaluated changes in calcium levels due to elevation of reactive oxygen species and monitored their effects on activation of cellular transcription factors.
