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Watching the Progression of Alzheimer's
Inspired by a colleague who runs the weblog “Tales of Hoffman,” the current cover and lead article in the Journal of Neuroscience (Dynamics of Gray Matter Loss in Alzheimer's Disease) shows a color-coded brain image that demonstrates the pattern of gray matter loss on the medial surface of the right brain hemisphere in a group of 17 patients with mild to moderate  Alzheimer's Disease. Red colors, in paralimbic and cingulate brain regions, denote areas with greatest gray matter loss, whereas cooler colors (yellow and blue) denote minimal or no gray matter loss. These color-coded maps reveal the spatial pattern of deficits in Alzheimer's disease, and they can help understand how the disease progresses in the human brain.
This is dramatically depicted in an animated sequence of time lapse MRI images that show brain tissue loss over a 2 year period.
Animation sequence
4:58:17 PM 
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