Only one 16 seed has ever beaten a 1 seed in the NCAA tournament. It's something that I would like to forget, but someone always reminds me that the 1998 Stanford women were the unlucky 1 seed. In defense of that 98 squad, I'd like to point out that two starters (Kristen Folkl and Vanessa Nygaard) went down with injuries in the week before that game. With a handful of practices to adjust to a missing 30+ ppg, Stanford lost 71-67. If any 1 seed loses two starters to injury this week, feel free to pick the upset.