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 Sunday, August 4, 2002
Mice provide insight into bone metabolism disorders [EurekAlert!]
Could be a nice model for investigations into bome metabolism. The mice had much higher numbers of macrophages than normal. Since these cells can develop into bone-degrading cells, it was not a surprise that these mice developed symptoms similar to a bone disease called juvenile Paget's disease, characterized by thin bone and fractures. The interplay between the inflammatory system, such as macrophages, and bone will be a very important link. 1:12:33 PM 
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Feds: Security leaks must end. Federal officials implore researchers and hackers who find security vulnerabilities to disclose the information more responsibly. [CNET News.com]
But who is to determine what 'responsiblly' means? Some companies are informed of problems and do nothing to fix them. For some it may be cheapere to threaten lawsuits than to fix the problem. SOme sort of standard should be used. 12:53:10 PM
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And I Can Link To It!. A weblog devoted to tracking sites that don't understand the web:
"Don't Link to Us! links to sites that attempt to impose substantial restrictions on other sites that link to them. The Linking Policy for Don't Link to Us! precludes us from requesting permission to link to a site, and compels us to link directly to the targeted page (i.e., a 'deep link') rather than to a site's home page. Descriptions of sites' linking policies generally are accurate (though often not complete) at the time they are posted here but are likely to change over time. On occasion a web site will modify its linking policy in response to public ridicule. Perhaps their appearance in Don't Link to Us! will help encourage some of these sites to move forward into the 20th century." [The Shifted Librarian]
Another example of how the net routes around percieved damage. There are much easier ways to control and prevent deep-linking than telling people not to. 12:38:00 PM
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InfoWorld: Fair use or foul play? I have found myself frequently raising this example in correspondence with readers about abuses of traditional fair use, free speech, and first-sale rights under the DMCA. With Congress considering even nastier laws that would hardwire copyright-holder protections into all types of digital devices, readers see many complex and troubling issues on the horizon. [Tomalak's Realm]
Nice take on our Brave New World of digital control by the government and the media companies. 12:28:09 PM
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Five reasons to invest in biotech stocks. National Post Online Aug 4 2002 12:31PM ET [Moreover - moreover...]
A good article with some very funny reasons. Mt favorite is # 3: Early stage biotech companies with drugs still awaiting regulatory approval: No revenues = No possibility of accounting fraud! 12:11:56 PM
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Christensen and Collins on Leadership. Clay Christensen is the author of "The Innovator's Dilemma". Jim Collins is the author of "Guilt to Last" and "Good to Great". Business 2.0 - gets the two to discuss - What Makes a Great Leader?. Christensen: Breaking an old business model is always going to require leaders to follow [E M E R G I C . o r g]
I've read Christensen's book. I'll have to check out Collins'. This is an incredible discussion between 2 men, one who examined why great companies failed and the other who looked at how middling companies achieved success. There are some differences but some extremely important similarities: Non-charasmatic CEOs; willing to go on gut istincts rather than market research; the importance of the right questions, not the right answers; creating cultures, not hierarchies. Fascinating and relevant stuff, whether you work in steel or in biotech. 12:09:18 PM
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Merck says it's joining Lake Union biotech hub. Seattle Times Aug 4 2002 1:32AM ET [Moreover - moreover...]
The Lake Union area looks like it will be quite a hub of bitech. Immunex/Amgen will eventually move into its Helix project just a few miles away. There will be a huge concnetration of biotech researchers in a very small area. Examples include the UW, Zymogenetics, Rosetta, Immunex/Amgen, Institute of Sysytems Biology, the Fred Hutch. Hope there are some good job opportunities. 11:57:45 AM
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Well, my son and I finally got to see Freddy Garcia win big and the Mariner's score lots of runs. Enough of these 1 run ball games. I wanted a blowout so we could really enjoy the ambience at Safeco. We got there early and had a chance to tour the new football stadium. It is pretty nice for a football stadium but it lacks a lot of what makes Safeco so special. The most important is that at Safeco you can still see and hear the game while strolling around getting food. The football stadium is like all the rest. If you go get food, you no longer can see the action. Plus, you get to be outside in the Seattle drizzle in the winter. Not a lot of fun ;-) 11:30:26 AM
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